TB10Cs4H3 snoRNA

TB10Cs4H3 is a member of the H/ACA-like class of non-coding RNA (ncRNA) molecule that guide the sites of modification of uridines to pseudouridines of substrate RNAs. It is known as a small nucleolar RNA (snoRNA) thus named because of its cellular localization in the nucleolus of the eukaryotic cell. TB10Cs4H3 is predicted to guide the pseudouridylation of LSU5 ribosomal RNA (rRNA) at residue Ψ1773.^[1]

References

^ Liang, XH; Uliel, S; Hury, A; Barth, S; Doniger, T; Unger, R; Michaeli, S (May 2005). "A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification". RNA. 11 (5): 619–45. doi:10.1261/rna.7174805. PMC 1370750. PMID 15840815.

[1] Liang, XH; Uliel, S; Hury, A; Barth, S; Doniger, T; Unger, R; Michaeli, S (May 2005). "A genome-wide analysis of C/D and H/ACA-like small nucleolar RNAs in Trypanosoma brucei reveals a trypanosome-specific pattern of rRNA modification". RNA. 11 (5): 619–45. doi:10.1261/rna.7174805. PMC 1370750. PMID 15840815.

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