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TARS (gene)

From Wikipedia, the free encyclopedia
TARS1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTARS1, ThrRS, threonyl-tRNA synthetase, TARS, threonyl-tRNA synthetase 1, TTD7
External IDsOMIM: 187790; MGI: 106314; HomoloGene: 11852; GeneCards: TARS1; OMA:TARS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001258437
NM_001258438
NM_152295

NM_033074

RefSeq (protein)

NP_001245366
NP_001245367
NP_689508

NP_149065

Location (UCSC)Chr 5: 33.44 – 33.47 MbChr 15: 11.38 – 11.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Threonyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the TARS gene.[5]

Aminoacyl tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113407Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022241Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: TARS threonyl-tRNA synthetase".

Further reading

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