TAGLN3

TAGLN3
Identifiers
Aliases	TAGLN3, NP22, NP24, NP25, transgelin 3
External IDs	OMIM: 607953; MGI: 1926784; HomoloGene: 22337; GeneCards: TAGLN3; OMA:TAGLN3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	112,013,887 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	45,544,971 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; right frontal lobe; ; Brodmann area 10; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; ganglionic eminence; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; pontine nuclei; ; lateral septal nucleus; ; lobe of cerebellum; ; cerebellar vermis; ; medial vestibular nucleus; ; ventromedial nucleus; ; superior frontal gyrus; ; lateral hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin filament binding;
Cellular component	nucleus; myelin sheath;
Biological process	central nervous system development; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	29114
	56370
	ENSG00000144834
	ENSMUSG00000022658
	Q9UI15
	Q9R1Q8
	NM_013259; NM_001008272; NM_001008273
	NM_019754
	NP_001008273; NP_001008274; NP_037391
	NP_062728
	Wikidata
View/Edit Human	View/Edit Mouse

Transgelin-3 or neuron protein NP25 is a protein that is in the nerve cells of humans, rats, mice, and chickens. It is encoded by the TAGLN3 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000144834 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022658 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ren WZ, Ng GY, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC (Jul 1994). "The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations". Brain Res Mol Brain Res. 22 (1–4): 173–85. doi:10.1016/0169-328X(94)90045-0. PMID 8015377.
^ Fan L, Jaquet V, Dodd PR, Chen W, Wilce PA (Mar 2001). "Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain". J Neurochem. 76 (5): 1275–81. doi:10.1046/j.1471-4159.2001.00176.x. PMID 11238712. S2CID 26310150.
^ "Entrez Gene: TAGLN3 transgelin 3".

Ito M, Depaz I, Wilce P, et al. (2005). "Expression of human neuronal protein 22, a novel cytoskeleton-associated protein, was decreased in the anterior cingulate cortex of schizophrenia". Neurosci. Lett. 378 (3): 125–30. doi:10.1016/j.neulet.2004.12.079. PMID 15781144. S2CID 10926640.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Depaz I, Ito M, Matsumoto I, et al. (2004). "Expression of hNP22 is altered in the frontal cortex and hippocampus of the alcoholic human brain" (PDF). Alcohol. Clin. Exp. Res. 27 (9): 1481–8. doi:10.1097/01.ALC.0000086060.18032.59. PMID 14506410.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Mol. Vis. 8: 196–204. PMID 12107411.
Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000144834 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022658 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8015377-5] Ren WZ, Ng GY, Wang RX, Wu PH, O'Dowd BF, Osmond DH, George SR, Liew CC (Jul 1994). "The identification of NP25: a novel protein that is differentially expressed by neuronal subpopulations". Brain Res Mol Brain Res. 22 (1–4): 173–85. doi:10.1016/0169-328X(94)90045-0. PMID 8015377.

[pmid11238712-6] Fan L, Jaquet V, Dodd PR, Chen W, Wilce PA (Mar 2001). "Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain". J Neurochem. 76 (5): 1275–81. doi:10.1046/j.1471-4159.2001.00176.x. PMID 11238712. S2CID 26310150.

[entrez-7] "Entrez Gene: TAGLN3 transgelin 3".

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References

Further reading