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Sutezolid

From Wikipedia, the free encyclopedia
Sutezolid
Names
Preferred IUPAC name
N-({(5S)-3-[3-Fluoro-4-(thiomorpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.237.103 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
    Key: FNDDDNOJWPQCBZ-ZDUSSCGKSA-N
  • InChI=1/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
    Key: FNDDDNOJWPQCBZ-ZDUSSCGKBM
  • CC(=O)NC[C@H]1CN(C(=O)O1)c2ccc(c(c2)F)N3CCSCC3
Properties
C16H20FN3O3S
Molar mass 353.41 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Sutezolid (PNU-100480, PF-02341272) is an oxazolidinone antibiotic currently in development as a treatment for extensively drug-resistant tuberculosis. It differs from linezolid by replacement of the morpholine oxygen with a sulfur atom.

Notes

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