Staphylococcus-1 RNA motif
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| Staphylococcus-1 | |
|---|---|
 Consensus secondary structure and sequence conservation of Staphylococcus-1 RNA | |
| Identifiers | |
| Symbol | Staphylococcus-1 |
| Rfam | RF03112 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
The Staphylococcus-1 RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1] A Staphylococcus-1 motif RNAs is found in Staphylococcus species CAG-324, which has not yet (as of 2018) been more precisely classified. Other examples of Staphylococcus-1 RNAs are present in metagenomic sequences that do not correspond to a classified organism. It is assumed that the organism corresponding to these sequences are related to the Staphylococcus species.
Most Staphylococcus-1 RNAs are found in the apparent 5′ untranslated regions (5′ UTRs) of genes whose protein products exhibit a borderline similarity to HNH endonucleases. This genetic arrangement could suggest that Staphylococcus-1 RNAs function as cis-regulatory elements. However, one Staphylococcus-1 RNA is not located in a 5′ UTR calls this hypothesis into question, and suggests that the RNAs more likely function as small RNAs.
References
[edit]- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.