Somatostatin family
| Somatostatin/cortistatin family | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbol | Somatostatin | ||||||||||
| Pfam | PF03002 | ||||||||||
| InterPro | IPR004250 | ||||||||||
| |||||||||||
The somatostatin family is a protein family with somatostatin as titular member, a hormone which inhibits the release of the pituitary somatotropin (growth hormone) and inhibits the release of glucagon and insulin from the pancreas of fasted animals. Cortistatin is a cortical neuropeptide with neuronal depressant and sleep-modulating properties.[1]
Human proteins from this family
[edit]- Cortistatin (CORT)
- Somatostatin (SST)
References
[edit]- ^ De Lecea L, Danielson PE, Criado JR, Prospero-garcia O, Gautvik KM, Schweitzer P, Dunlop CL, Siggins GR, Henriksen SJ, Sutcliffe JG (1996). "A cortical neuropeptide with neuronal depressant and sleep-modulating properties". Nature. 381 (6579): 242–245. Bibcode:1996Natur.381..242D. doi:10.1038/381242a0. PMID 8622767. S2CID 3931102.