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ST8SIA6

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ST8SIA6
Identifiers
AliasesST8SIA6, SIA8F, SIAT8F, ST8SIA-VI, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6, ST8SiaVI, SIAT8-F
External IDsOMIM: 610139; MGI: 2386797; HomoloGene: 17112; GeneCards: ST8SIA6; OMA:ST8SIA6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001004470
NM_001345961

NM_145838

RefSeq (protein)

NP_001004470
NP_001332890

NP_665837

Location (UCSC)Chr 10: 17.32 – 17.45 MbChr 2: 13.66 – 13.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 is a protein that in humans is encoded by the ST8SIA6 gene. [5]

Function

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Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148488Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003418Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6". Retrieved 2017-02-02.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.