SPEF1

SPEF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2EE7
Identifiers
Aliases	SPEF1, C20orf28, CLAMP, SPEF1A, sperm flagellar 1
External IDs	OMIM: 610674; MGI: 3513546; HomoloGene: 15741; GeneCards: SPEF1; OMA:SPEF1 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) Band 20p13 Start 3,777,504 bp End 3,781,448 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 F1|2 Start 131,012,181 bp End 131,029,202 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube olfactory zone of nasal mucosa caudate nucleus putamen nucleus accumbens epithelium of bronchus bronchial epithelial cell gonad dorsal motor nucleus of vagus nerve prefrontal cortex Top expressed in Ileal epithelium olfactory epithelium choroid plexus of fourth ventricle ventricular zone spermatocyte spermatid ganglionic eminence saccule Epithelium of choroid plexus right lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding microtubule binding molecular function Cellular component cytoplasm axoneme cell projection motile cilium cilium cytoskeleton cellular component Biological process negative regulation of microtubule depolymerization cell migration biological process cilium-dependent cell motility regulation of cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25876 70997 Ensembl ENSG00000101222 ENSMUSG00000027329 UniProt Q9Y4P9 Q99JL1 RefSeq (mRNA) NM_015417 NM_027641 RefSeq (protein) NP_056232 NP_081917 Location (UCSC) Chr 20: 3.78 – 3.78 Mb Chr 2: 131.01 – 131.03 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Sperm flagellar protein 1 is a protein that in humans is encoded by the SPEF1 gene.

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Dougherty GW, Adler HJ, Rzadzinska A, et al. (2006). "CLAMP, a novel microtubule-associated protein with EB-type calponin homology". Cell Motil. Cytoskeleton. 62 (3): 141–56. doi:10.1002/cm.20093. PMID 16206169.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.