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Protein-coding gene in the species Homo sapiens
Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene .[ 5] [ 6]
The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain . Transcript variants for this gene have been described, but their full-length nature has not been determined.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000147481 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025909 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V (Jun 2000). "Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells" . J Biol Chem . 275 (21): 15851–60. doi :10.1074/jbc.M000439200 . PMID 10747910 .
^ a b "Entrez Gene: SNTG1 syntrophin, gamma 1" .
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