SNN (gene)

SNN
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1ZZA
Identifiers
Aliases	SNN, stannin
External IDs	OMIM: 603032; MGI: 1276549; HomoloGene: 81710; GeneCards: SNN; OMA:SNN - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16p13.13 Start 11,668,455 bp End 11,679,152 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band 16|16 A1 Start 10,878,809 bp End 10,892,849 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus endothelial cell external globus pallidus entorhinal cortex Brodmann area 23 Region I of hippocampus proper putamen caudate nucleus superior frontal gyrus postcentral gyrus Top expressed in mesenteric lymph nodes olfactory tubercle ventricular zone medial ganglionic eminence globus pallidus substantia nigra superior frontal gyrus otolith organ dentate gyrus of hippocampal formation granule cell utricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding Cellular component mitochondrial outer membrane membrane mitochondrion cytoplasm integral component of membrane Biological process response to toxic substance Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8303 20621 Ensembl ENSG00000184602 ENSMUSG00000037972 UniProt O75324 P61807 RefSeq (mRNA) NM_003498 NM_009223 RefSeq (protein) NP_003489 NP_033249 Location (UCSC) Chr 16: 11.67 – 11.68 Mb Chr 16: 10.88 – 10.89 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Stannin is a protein that in humans is encoded by the SNN gene.

Further reading

• Toggas SM, Krady JK, Billingsley ML (July 1992). "Molecular neurotoxicology of trimethyltin: identification of stannin, a novel protein expressed in trimethyltin-sensitive cells". Molecular Pharmacology. 42 (1): 44–56. PMID 1635553.
• Dejneka NS, Patanow CM, Polavarapu R, Toggas SM, Krady JK, Billingsley ML (December 1997). "Localization and characterization of stannin: relationship to cellular sensitivity to organotin compounds". Neurochemistry International. 31 (6): 801–15. doi:10.1016/S0197-0186(97)00034-X. PMID 9413842. S2CID 23369837.
• Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (May 1999). "Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes". Blood. 93 (10): 3418–31. doi:10.1182/blood.V93.10.3418.410k23_3418_3431. PMID 10233894.
• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Ballif BA, Villén J, Beausoleil SA, Schwartz D, Gygi SP (November 2004). "Phosphoproteomic analysis of the developing mouse brain". Molecular & Cellular Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.