SH3BGRL

SH3BGRL
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1U6T, 1WRY
Identifiers
Aliases	SH3BGRL, HEL-S-115, SH3BGR, SH3 domain binding glutamate rich protein like
External IDs	OMIM: 300190; MGI: 1930849; HomoloGene: 2275; GeneCards: SH3BGRL; OMA:SH3BGRL - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	81,298,547 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	108,241,479 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; tail of epididymis; ; monocyte; ; superficial temporal artery; ; saphenous vein; ; trabecular bone; ; urethra; ; lactiferous duct; ; germinal epithelium; ; popliteal artery;
	Top expressed in
	medial ganglionic eminence; ; tunica media of zone of aorta; ; ascending aorta; ; olfactory epithelium; ; Epithelium of choroid plexus; ; aortic valve; ; carotid body; ; left lung lobe; ; calvaria; ; submandibular gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding;
Cellular component	cytoplasm; extracellular exosome; nucleus; extracellular space;
Biological process	positive regulation of signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	6451
	56726
	ENSG00000131171
	ENSMUSG00000031246
	O75368
	Q9JJU8
	NM_003022
	NM_019989
	NP_003013
	NP_064373
	Wikidata
View/Edit Human	View/Edit Mouse

SH3 domain-binding glutamic acid-rich-like protein is a protein that in humans is encoded by the SH3BGRL gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000131171 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031246 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Egeo A, Mazzocco M, Arrigo P, Vidal-Taboada JM, Oliva R, Pirola B, Giglio S, Rasore-Quartino A, Scartezzini P (Jul 1998). "Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene". Biochem Biophys Res Commun. 247 (2): 302–6. doi:10.1006/bbrc.1998.8763. PMID 9642120.
^ "Entrez Gene: SH3BGRL SH3 domain binding glutamic acid-rich protein like".

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Drutel G, Arrang JM, Diaz J, et al. (1996). "Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart". Recept. Channels. 3 (1): 33–40. PMID 8589991.
Yin L, Xiang Y, Zhu DY, et al. (2006). "Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins". Proteins. 61 (1): 213–6. doi:10.1002/prot.20523. PMID 16080146.
Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876–84. doi:10.1002/pmic.200401239. PMID 16130169. S2CID 26007149.
Majid SM, Liss AS, You M, Bose HR (2006). "The suppression of SH3BGRL is important for v-Rel-mediated transformation". Oncogene. 25 (5): 756–68. doi:10.1038/sj.onc.1209107. PMID 16186799. S2CID 42806147.
Schulze WX, Deng L, Mann M (2006). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Mol. Syst. Biol. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC 1681463. PMID 16729043.

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