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S-methyl-5'-thioadenosine deaminase

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S-methyl-5'-thioadenosine deaminase
Identifiers
EC no.3.5.4.31
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31, MTA deaminase, 5-methylthioadenosine deaminase) is an enzyme with systematic name S-methyl-5'-thioadenosine amidohydrolase.[1] This enzyme catalyses the following chemical reaction

S-methyl-5'-thioadenosine + H2O 5'-S-methyl-5'-thioinosine + NH3

The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28).

References

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  1. ^ Hermann JC, Marti-Arbona R, Fedorov AA, Fedorov E, Almo SC, Shoichet BK, Raushel FM (August 2007). "Structure-based activity prediction for an enzyme of unknown function". Nature. 448 (7155): 775–9. doi:10.1038/nature05981. PMC 2254328. PMID 17603473.
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