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Restriction endonuclease BsobI/AvaI

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Endonuc-BsobI
restriction enzyme bsobi/dna complex structure: encirclement of the dna and histidine-catalyzed hydrolysis within a canonical restriction enzyme fold
Identifiers
SymbolEndonuc-BsobI
PfamPF09194
InterProIPR015277
SCOP21dc1 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

In molecular biology, the restriction endonuclease BsobI/AvaI family of enzymes includes the AvaI and BsoBI restriction endonucleases from Anabaena variabilis and Bacillus stearothermophilus, both of which recognise the double-stranded sequence CYCGRG (where Y = T/C, and R = A/G) and cleave after C-1.[1]

References

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  1. ^ van der Woerd MJ, Pelletier JJ, Xu S, Friedman AM (February 2001). "Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis". Structure. 9 (2): 133–44. doi:10.1016/S0969-2126(01)00564-0. PMID 11250198.
This article incorporates text from the public domain Pfam and InterPro: IPR015277