Ras association domain family member 7

RASSF7
Identifiers
Aliases	RASSF7, C11orf13, HRAS1, HRC1, Ras association domain family member 7, CFAP88, FAP88
External IDs	OMIM: 143023; MGI: 1914235; HomoloGene: 2595; GeneCards: RASSF7; OMA:RASSF7 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.5 Start 560,404 bp End 564,025 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F5 Start 140,795,773 bp End 140,798,571 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube mucosa of transverse colon right lobe of liver right lung body of pancreas right hemisphere of cerebellum human kidney olfactory zone of nasal mucosa skin of leg skin of abdomen Top expressed in esophagus transitional epithelium of urinary bladder lip right kidney intestinal villus yolk sac duodenum jejunum proximal tubule left colon More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm cytoskeleton microtubule organizing center Biological process signal transduction apoptotic process regulation of microtubule cytoskeleton organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8045 66985 Ensembl ENSG00000273859 ENSG00000099849 ENSMUSG00000038618 UniProt Q02833 Q9DD19 RefSeq (mRNA) NM_001143993 NM_001143994 NM_003475 NM_025886 RefSeq (protein) NP_001137465 NP_001137466 NP_003466 NP_080162 Location (UCSC) Chr 11: 0.56 – 0.56 Mb Chr 7: 140.8 – 140.8 Mb PubMed search
Wikidata
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Ras association domain family member 7 is a protein that in humans is encoded by the RASSF7 gene.

Further reading

• Iarmolinskiĭ DG, Kartel NA, Ermak G, Demidchik IuE, Figge J (2004). "[Study of HRas1 minisatellite frequencies in children with thyroid papillary cancer]". Tsitol. Genet. (in Russian). 38 (1): 9–14. PMID 15098441.
• Lescai F, Blanché H, Nebel A, Beekman M, Sahbatou M, Flachsbart F, Slagboom E, Schreiber S, Sorbi S, Passarino G, Franceschi C (2009). "Human longevity and 11p15.5: a study in 1321 centenarians". Eur. J. Hum. Genet. 17 (11): 1515–9. doi:10.1038/ejhg.2009.54. PMC 2986679. PMID 19367319.
• Recino A, Sherwood V, Flaxman A, Cooper WN, Latif F, Ward A, Chalmers AD (2010). "Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis". Biochem. J. 430 (2): 207–13. doi:10.1042/BJ20100883. PMC 2922839. PMID 20629633.
• Takahashi S, Ebihara A, Kajiho H, Kontani K, Nishina H, Katada T (2011). "RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7". Cell Death Differ. 18 (4): 645–55. doi:10.1038/cdd.2010.137. PMC 3131899. PMID 21278800.
• Djos A, Martinsson T, Kogner P, Carén H (2012). "The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma". Mol. Cancer. 11: 40. doi:10.1186/1476-4598-11-40. PMC 3493266. PMID 22695170.
• Gulsen T, Hadjicosti I, Li Y, Zhang X, Whitley PR, Chalmers AD (2016). "Truncated RASSF7 promotes centrosomal defects and cell death". Dev. Biol. 409 (2): 502–17. doi:10.1016/j.ydbio.2015.11.001. PMID 26569555.