RRS1

RRS1
Identifiers
Aliases	RRS1, ribosome biogenesis regulator homolog, ribosome biogenesis regulator 1 homolog
External IDs	OMIM: 618311; MGI: 1929721; HomoloGene: 41014; GeneCards: RRS1; OMA:RRS1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	66,430,733 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	9,617,680 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; synovial membrane; ; body of pancreas; ; skeletal muscle tissue; ; muscle of thigh; ; mucosa of transverse colon; ; monocyte; ; left uterine tube; ; body of stomach; ; left ventricle;
	Top expressed in
	epiblast; ; otic vesicle; ; cingulate gyrus; ; upper arm; ; mesenchyme; ; epithelium of small intestine; ; autopod region; ; intestinal villus; ; amygdala; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding; 5S rRNA binding;
Cellular component	condensed nuclear chromosome; nucleolus; nucleus; endoplasmic reticulum; preribosome, large subunit precursor; fibrillar center;
Biological process	ribosomal large subunit export from nucleus; mitotic metaphase plate congression; ribosome biogenesis; hematopoietic progenitor cell differentiation; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal large subunit assembly; ribosomal large subunit biogenesis; protein localization to nucleolus; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	23212
	59014
	ENSG00000179041
	ENSMUSG00000061024
	Q15050
	Q9CYH6
	NM_015169
	NM_021511
	NP_055984
	NP_067486
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosome biogenesis regulatory protein homolog is a protein that in humans is encoded by the RRS1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179041 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061024 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi:10.1093/dnares/2.1.37. PMID 7788527.
^ Tsuno A, Miyoshi K, Tsujii R, Miyakawa T, Mizuta K (Mar 2000). "RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae". Mol Cell Biol. 20 (6): 2066–74. doi:10.1128/MCB.20.6.2066-2074.2000. PMC 110823. PMID 10688653.
^ "Entrez Gene: RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.

This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179041 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061024 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7788527-5] Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi:10.1093/dnares/2.1.37. PMID 7788527.

[pmid10688653-6] Tsuno A, Miyoshi K, Tsujii R, Miyakawa T, Mizuta K (Mar 2000). "RRS1, a Conserved Essential Gene, Encodes a Novel Regulatory Protein Required for Ribosome Biogenesis in Saccharomyces cerevisiae". Mol Cell Biol. 20 (6): 2066–74. doi:10.1128/MCB.20.6.2066-2074.2000. PMC 110823. PMID 10688653.

[entrez-7] "Entrez Gene: RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)".

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References

Further reading