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Enzyme found in humans
RPS6KA2 Identifiers Aliases RPS6KA2 External IDs OMIM : 601685 ; MGI : 1342290 ; HomoloGene : 100680 ; GeneCards : RPS6KA2 ; OMA :RPS6KA2 - orthologs RNA expression patternBgee Human Mouse (ortholog)Top expressed in inferior olivary nucleus lower lobe of lung internal globus pallidus dorsal motor nucleus of vagus nerve inferior ganglion of vagus nerve C1 segment optic nerve right lung corpus callosum superior vestibular nucleus
Top expressed in granulocyte muscle of thigh neural layer of retina tail of embryo superior frontal gyrus dentate gyrus of hippocampal formation granule cell primary visual cortex genital tubercle lens ventricular zone
More reference expression data
BioGPS
Wikidata
Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene .[ 5] [ 6]
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine and threonine kinases . This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen -activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation . Alternate transcriptional splice variants, encoding different isoforms , have been characterized.[ 6]
RPS6KA2 has been shown to interact with MAPK3 [ 7] [ 8] MAPK1 .[ 7] [ 8]
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Activity Regulation Classification Kinetics Types
