RNF39

RNF39
Identifiers
Aliases	RNF39, HZF, HZFW, LIRF, ring finger protein 39, FAP216
External IDs	OMIM: 607524; MGI: 2156378; HomoloGene: 11891; GeneCards: RNF39; OMA:RNF39 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,075,849 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	37,258,878 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; minor salivary glands; ; vagina; ; olfactory zone of nasal mucosa; ; prostate; ; right uterine tube; ; testicle; ; body of stomach; ; ectocervix;
	Top expressed in
	skin of abdomen; ; lip; ; esophagus; ; skin of external ear; ; skin of back; ; conjunctival fornix; ; hair follicle; ; decidua; ; gastrula; ; right lung lobe;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding;
Cellular component	cytoplasm; cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
	80352
	386454
ENSG00000230467; ENSG00000206500; ENSG00000204618; ENSG00000237733; ENSG00000227171;
	ENSG00000235022; ENSG00000236967; ENSG00000230332
	ENSMUSG00000036492
	Q9H2S5
	n/a
	NM_170770; NM_025236; NM_170769
	NM_001099632
	NP_079512; NP_739575
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene.^[5]^[6]^[7]

This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms.^[7]

References

^ ^a ^b ^c ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 GRCh38: Ensembl release 89: ENSG00000230467, ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036492 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Coriton O, Lepourcelet M, Hampe A, Galibert F, Mosser J (Dec 2000). "Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes". Mamm Genome. 11 (12): 1127–31. doi:10.1007/s003350010213. PMID 11130983. S2CID 22881226.
^ Matsuo R, Asada A, Fujitani K, Inokuchi K (Nov 2001). "LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein". Biochem Biophys Res Commun. 289 (2): 479–84. doi:10.1006/bbrc.2001.5975. PMID 11716498.
^ ^a ^b "Entrez Gene: RNF39 ring finger protein 39".

Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Orimo A, Yamagishi T, Tominaga N, et al. (2000). "Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC". Biochem. Biophys. Res. Commun. 276 (1): 45–51. doi:10.1006/bbrc.2000.3380. PMID 11006080.
Hidaka M, Caruana G, Stanford WL, et al. (2000). "Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells". Mech. Dev. 90 (1): 3–15. doi:10.1016/S0925-4773(99)00234-8. PMID 10585558. S2CID 673064.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

[refGRCh38Ensembl-1] ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 GRCh38: Ensembl release 89: ENSG00000230467, ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036492 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11130983-5] Coriton O, Lepourcelet M, Hampe A, Galibert F, Mosser J (Dec 2000). "Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes". Mamm Genome. 11 (12): 1127–31. doi:10.1007/s003350010213. PMID 11130983. S2CID 22881226.

[pmid11716498-6] Matsuo R, Asada A, Fujitani K, Inokuchi K (Nov 2001). "LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein". Biochem Biophys Res Commun. 289 (2): 479–84. doi:10.1006/bbrc.2001.5975. PMID 11716498.

[entrez-7] "Entrez Gene: RNF39 ring finger protein 39".

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[6]

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References

Further reading