Jump to content

RBM6

From Wikipedia, the free encyclopedia

RBM6
Identifiers
AliasesRBM6, 3G2, DEF-3, DEF3, HLC-11, NY-LU-12, g16, RNA binding motif protein 6
External IDsOMIM: 606886; MGI: 1338037; HomoloGene: 31336; GeneCards: RBM6; OMA:RBM6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_011251
NM_029169

RefSeq (protein)

n/a

Location (UCSC)Chr 3: 49.94 – 50.1 MbChr 9: 107.65 – 107.75 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA-binding protein 6 is a protein that in humans is encoded by the RBM6 gene.[5][6] RBM6 orthologs[7] have been identified in all mammals for which complete genome data are available.

RBM6 splicing factor interacts with the DNA repair protein RAD51, and is also recruited to DNA double-strand breaks where it promotes homologous recombinational repair.[8]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000004534Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032582Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Timmer T, Terpstra P, van den Berg A, Veldhuis PM, Ter Elst A, Voutsinas G, Hulsbeek MM, Draaijers TG, Looman MW, Kok K, Naylor SL, Buys CH (Aug 1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3". Eur J Hum Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.
  6. ^ "Entrez Gene: RBM6 RNA binding motif protein 6".
  7. ^ "OrthoMaM phylogenetic marker: RBM6 coding sequence". Archived from the original on 2016-03-03. Retrieved 2009-12-09.
  8. ^ Awwad SW, Darawshe MM, Machour FE, Arman I, Ayoub N (2023). "Recruitment of RBM6 to DNA Double-Strand Breaks Fosters Homologous Recombination Repair". Mol Cell Biol. 43 (3): 130–142. doi:10.1080/10985549.2023.2187105. PMC 10038030. PMID 36941773.

Further reading

[edit]
[edit]