From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Rap1 GTPase-GDP dissociation stimulator 1 is an enzyme that in humans is encoded by the RAP1GDS1 gene .[ 5] [ 6] [ 7]
RAP1GDS1 has been shown to interact with KIFAP3 ,[ 8] HRAS [ 9] RHOA .[ 9]
^ a b c GRCh38: Ensembl release 89: ENSG00000138698 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028149 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Riess O, Epplen C, Siedlaczck I, Epplen JT (Jan 1994). "Chromosomal assignment of the human smg GDP dissociation stimulator gene to human chromosome 4q21-q25". Hum Genet . 92 (6): 629–30. doi :10.1007/BF00420952 . PMID 8262526 . S2CID 21189125 . ^ Tew GW, Lorimer EL, Berg TJ, Zhi H, Li R, Williams CL (Jan 2008). "SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma" . J Biol Chem . 283 (2): 963–76. doi :10.1074/jbc.M707526200 PMID 17951244 . ^ "Entrez Gene: RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1" .^ Shimizu K, Kawabe H, Minami S, Honda T, Takaishi K, Shirataki H, Takai Y (Oct 1996). "SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase" . J. Biol. Chem . 271 (43): 27013–7. doi :10.1074/jbc.271.43.27013 ISSN 0021-9258 . PMID 8900189 . ^ a b Vikis HG, Stewart Scott, Guan Kun-Liang (Apr 2002). "SmgGDS displays differential binding and exchange activity towards different Ras isoforms". Oncogene . 21 (15): 2425–32. doi :10.1038/sj.onc.1205306 . ISSN 0950-9232 . PMID 11948427 . S2CID 6647800 .
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