RAB37

RAB37
Identifiers
Aliases	RAB37, member RAS oncogene family
External IDs	OMIM: 609956; MGI: 1929945; HomoloGene: 23303; GeneCards: RAB37; OMA:RAB37 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,747,335 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,053,062 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; granulocyte; ; monocyte; ; blood; ; nasal epithelium; ; spleen; ; bone marrow cells; ; right lobe of liver; ; endothelial cell;
	Top expressed in
	islet of Langerhans; ; granulocyte; ; lateral geniculate nucleus; ; anterior horn of spinal cord; ; medial dorsal nucleus; ; medial geniculate nucleus; ; retinal pigment epithelium; ; cerebellar cortex; ; facial motor nucleus; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cytoplasmic vesicle; endoplasmic reticulum-Golgi intermediate compartment; azurophil granule membrane; specific granule membrane; endosome; plasma membrane; synaptic vesicle; secretory granule membrane; intracellular anatomical structure;
Biological process	protein transport; neutrophil degranulation; vesicle docking involved in exocytosis; protein secretion; protein localization to plasma membrane; regulation of exocytosis; intracellular protein transport; Rab protein signal transduction; small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	326624
	58222
	ENSG00000172794
	ENSMUSG00000020732
	Q96AX2
	Q9JKM7
NM_001006637; NM_001006638; NM_001163989; NM_001163990; NM_175738;
	NM_001330471
	NM_001163753; NM_021411
	NP_001006639; NP_001157461; NP_001157462; NP_001317400; NP_783865
	NP_001157225; NP_067386
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.^[5]^[6]

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172794 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020732 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.
^ ^a ^b "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172794 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020732 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10722846-5] Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett. 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846. S2CID 38218555.

[entrez-6] "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

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References

Further reading