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Psilostachyin

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Psilostachyin

Psilostachyin A

Psilostachyin B

Psilostachyin C
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • A: InChI=1S/C15H20O5/c1-8-4-5-10-9(2)13(17)19-12(10)14(3,18)15(8)7-6-11(16)20-15/h8,10,12,18H,2,4-7H2,1,3H3/t8-,10-,12+,14-,15+/m0/s1
    Key: IRPFOXRBPHCCTG-JISBIHODSA-N
  • B: InChI=1S/C15H18O4/c1-8-4-5-10-9(2)14(17)18-13(10)15(3)11(8)6-7-12(16)19-15/h10,13H,2,4-7H2,1,3H3/t10-,13+,15+/m0/s1
    Key: IOGFBFUSBVLQMS-PSOPSSQASA-N
  • C: InChI=1S/C15H20O4/c1-8-4-5-10-9(2)14(17)18-13(10)15(3)11(8)6-7-12(16)19-15/h8,10-11,13H,2,4-7H2,1,3H3/t8-,10-,11-,13+,15+/m0/s1
    Key: FZYIWDQVFMUXPW-OEAYZANCSA-N
  • A: C[C@H]1CC[C@@H]2[C@H]([C@]([C@@]13CCC(=O)O3)(C)O)OC(=O)C2=C
  • B: CC1=C2CCC(=O)O[C@]2([C@H]3[C@@H](CC1)C(=C)C(=O)O3)C
  • C: C[C@H]1CC[C@@H]2[C@H]([C@]3([C@H]1CCC(=O)O3)C)OC(=O)C2=C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Psilostachyins are group of chemical compounds isolated from Ambrosia psilostachya.[1][2][3][4]

References

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  1. ^ Kagan, H. B; Miller, H. E; Renold, Walter; Lakshmikantham, M. V; Tether, L. R; Herz, Werner; Mabry, T. J (1966). "The Structure of Psilostachyin C, a New Sesquiterpene Dilactone from Ambrosia psilostachya DC". The Journal of Organic Chemistry. 31 (5): 1629–1632. doi:10.1021/jo01343a072.
  2. ^ Da Silva, C. F.; Batista, D. d. G. J.; De Araujo, J. S.; Batista, M. M.; Lionel, J.; De Souza, E. M.; Hammer, E. R.; Da Silva, P. B.; De Mieri, M.; Adams, M.; Zimmermann, S.; Hamburger, M.; Brun, R.; Schuhly, W.; Soeiro, M. d. N. C. (2013). "Activities of Psilostachyin a and Cynaropicrin against Trypanosoma cruzi in Vitro and in Vivo". Antimicrobial Agents and Chemotherapy. 57 (11): 5307–14. doi:10.1128/AAC.00595-13. PMC 3811247. PMID 23939901.
  3. ^ Raszeja, W.; Gill, St. (2009). "Isolation and Identification of Psilostachyin B from Ambrosia Artemisiifolia L". Planta Medica. 32 (8): 319–22. doi:10.1055/s-0028-1097606. PMID 594205.
  4. ^ Sülsen, Valeria P.; Frank, Fernanda M.; Cazorla, Silvia I.; Barrera, Patricia; Freixa, Blanca; Vila, Roser; Sosa, Miguel A.; Malchiodi, Emilio L.; Muschietti, Liliana V.; Martino, Virginia S. (2011). "Psilostachyin C: A natural compound with trypanocidal activity". International Journal of Antimicrobial Agents. 37 (6): 536–43. doi:10.1016/j.ijantimicag.2011.02.003. hdl:11336/198521. PMID 21497061.