Proline rich 5 like

PRR5L
Identifiers
Aliases	PRR5L, PROTOR2, proline rich 5 like
External IDs	OMIM: 611728; MGI: 1919696; HomoloGene: 11753; GeneCards: PRR5L; OMA:PRR5L - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	36,465,204 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	101,713,372 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; granulocyte; ; rectum; ; spleen; ; C1 segment; ; secondary oocyte; ; testicle; ; corpus callosum; ; monocyte; ; mucosa of sigmoid colon;
	Top expressed in
	hand; ; lumbar subsegment of spinal cord; ; molar; ; hair follicle; ; zygote; ; serosa of urinary bladder; ; primary oocyte; ; secondary oocyte; ; skin of hand; ; medullary collecting duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin protein ligase binding; protein binding;
Cellular component	TORC2 complex;
Biological process	TORC2 signaling; negative regulation of protein phosphorylation; positive regulation of phosphatidylinositol 3-kinase signaling; negative regulation of signal transduction; positive regulation of protein phosphorylation; regulation of fibroblast migration; cellular response to oxidative stress; positive regulation of mRNA catabolic process; positive regulation of intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
	79899
	72446
	ENSG00000135362
	ENSMUSG00000032841
	Q6MZQ0
	A2AVJ5
	NM_024841; NM_001160167; NM_001160168; NM_001160169
	NM_001083810; NM_001110849; NM_175181; NM_001355625
	NP_001153639; NP_001153640; NP_001153641; NP_079117
	NP_001077279; NP_001104319; NP_780390; NP_001342554
	Wikidata
View/Edit Human	View/Edit Mouse

Proline rich 5 like is a protein that in humans is encoded by the PRR5L gene. ^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135362 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032841 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Proline rich 5 like". Retrieved 2017-03-17.

Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR (2007). "Identification of Protor as a novel Rictor-binding component of mTOR complex-2". Biochem. J. 405 (3): 513–22. doi:10.1042/BJ20070540. PMC 2267312. PMID 17461779.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135362 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032841 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Proline rich 5 like". Retrieved 2017-03-17.

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References

Further reading