Portal:Medicine/Selected article/31, 2006

The menstrual cycle is a recurring cycle of physiological changes in the females of some animal species that is associated with reproductive fertility. Only human beings and the great apes experience a true menstrual cycle. Most placental mammals experience estrus instead. The menstrual cycle is under the control of the reproductive hormone system and is necessary for reproduction. In women, menstrual cycles occur typically on a monthly basis between puberty and menopause.

During the menstrual cycle, the sexually mature female body builds up the lining of the uterus with gradually increasing amounts of estrogen, and when this hormone reaches a critical level, estradiol is produced, and shortly thereafterward there is the stimulation of the ovaries with Follicle Stimulating Hormone, and luteinizing hormone. Follicles begin developing, and within a few days one "matures" into an ovum or egg. The ovary then releases this egg, (or occasionally two, which might result in dizygotic, or non-identical, twins) at the time of ovulation. The lining of the uterus, the endometrium, peaks shortly there afterward in a synchronised fashion. After ovulation, this lining changes to prepare for potential conception and implantation of the fertilized egg to establish a pregnancy. The hormone progesterone rises after ovulation, and peaks shortly thereafter. (More...)