Portal:Medicine/Did you know/16

• Snoezelen or "controlled multisensory stimulation" might be beneficial to people with autism and other developmental disabilities, dementia, and brain injury?
• The therapeutic index of a medication is a comparison of the amount that causes the therapeutic effect to the amount that causes toxic effects. Quantitatively, it is the ratio of the dose required to produce the desired therapeutic effect and the toxic dose. A commonly used measure of therapeutic index is the effective dose of a drug for 50% of the population (ED₅₀) divided by the lethal dose for 50% of the population (LD₅₀).
• ...that a toddler with a syndrome of rash (pictured), arthralgia/arthritis, abdominal pain and renal disease, preceded by a viral upper respiratory tract infection, is likely to have Henoch-Schönlein purpura?