Portal:History of science/Selected anniversaries/September 15
- 1596 - Death of Leonhard Rauwolf, German physician and botanist
- 1828 - Birth of Aleksandr Mikhailovich Butlerov, Russian chemist (d. 1886)
- 1830 - The Liverpool to Manchester railway line opens
- 1852 - Birth of Edward Bouchet, American physicist (d. 1918)
- 1883 - Birth of Esteban Terradas i Illa, Spanish mathematician and engineer (d. 1950)
- 1926 - Birth of Jean-Pierre Serre, French mathematician
- 1929 - Birth of Murray Gell-Mann, American physicist, Nobel Prize laureate
- 1947 - RCA releases the 12AX7 vacuum tube
- 1981 - The John Bull becomes the oldest operable steam locomotive in the world when the Smithsonian Institution operates it under its own power outside Washington, DC