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Phosphoglucomutase (glucose-cofactor)

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phosphoglucomutase (glucose-cofactor)
Identifiers
EC no.5.4.2.5
CAS no.37278-22-1
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In enzymology, a phosphoglucomutase (glucose-cofactor) (EC 5.4.2.5) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 1-phosphate ⇌ D-glucose 6-phosphate

Hence, this enzyme has one substrate, alpha-D-glucose 1-phosphate, and one product, D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is alpha-D-glucose 1,6-phosphomutase (glucose-cofactor). Other names in common use include glucose phosphomutase, and glucose-1-phosphate phosphotransferase. This enzyme has at least one effector, D-Glucose.

References

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  • FUJIMOTO A, INGRAM P, SMITH RA (1965). "D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6-PHOSPHOTRANSFERASE". Biochim. Biophys. Acta. 96: 91–101. doi:10.1016/0005-2787(65)90613-1. PMID 14285271.
  • Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.