Phloroisovalerophenone synthase
| phloroisovalerophenone synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.3.1.156 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a phloroisovalerophenone synthase (EC 2.3.1.156) is an enzyme that catalyzes the chemical reaction
- isovaleryl-CoA + 3 malonyl-CoA 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one
Thus, the two substrates of this enzyme are isovaleryl-CoA and malonyl-CoA, whereas its 3 products are CoASH, CO2, and 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is isovaleryl-CoA:malonyl-CoA acyltransferase. Other names in common use include valerophenone synthase, and 3-methyl-1-(trihydroxyphenyl)butan-1-one synthase.
References
[edit]- Verpoorte R (1997). "Enzymes from the biosynthesis of hop alpha and beta acids". Proc. 26th Congr. Eur. Brew. Conv.: 215–221.
- Zuurbier KW, Leser J, Berger T, Hofte AJ, Schröder G, Verpoorte R, Schröder J (December 1998). "4-Hydroxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates". Phytochemistry. 49 (7): 1945–51. doi:10.1016/S0031-9422(98)00346-X. PMID 9883590.
