Phenylalanine(histidine) transaminase
| phenylalanine(histidine) transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.58 | ||||||||
| CAS no. | 72560-98-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a phenylalanine(histidine) transaminase (EC 2.6.1.58) is an enzyme that catalyzes the chemical reaction
- L-phenylalanine + pyruvate phenylpyruvate + L-alanine
Thus, the two substrates of this enzyme are L-phenylalanine and pyruvate, whereas its two products are phenylpyruvate and L-alanine.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-phenylalanine:pyruvate aminotransferase. Other names in common use include phenylalanine (histidine) aminotransferase, phenylalanine(histidine):pyruvate aminotransferase, histidine:pyruvate aminotransferase, and L-phenylalanine(L-histidine):pyruvate aminotransferase.
References
[edit]Further reading
[edit]- Minatogawa Y, Noguchi T, Kido R (January 1977). "Species distribution and properties of hepatic phenylalanine (histidine):pyruvate aminotransferase". Hoppe-Seyler's Zeitschrift für Physiologische Chemie. 358 (1): 59–67. doi:10.1515/bchm2.1977.358.1.59. PMID 14070.
