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Peptidase inhibitor 15

From Wikipedia, the free encyclopedia
PI15
Identifiers
AliasesPI15, CRISP8, P24TI, P25TI, peptidase inhibitor 15
External IDsOMIM: 607076; MGI: 1934659; HomoloGene: 22935; GeneCards: PI15; OMA:PI15 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015886
NM_001324403

NM_053191

RefSeq (protein)

NP_001311332
NP_056970

NP_444421

Location (UCSC)Chr 8: 74.82 – 74.86 MbChr 1: 17.67 – 17.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Peptidase inhibitor 15 is a protein that in humans is encoded by the PI15 gene. [5]

Function

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This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000137558Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067780Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Peptidase inhibitor 15". Retrieved 2018-08-01.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.