Penflufen

Penflufen
Names
	IUPAC name 5-Fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]pyrazole-4-carboxamide
Identifiers
CAS Number	494793-67-8;
3D model (JSmol)	Interactive image;
PubChem CID	11674113;
UNII	8252E275KT;
	SMILES CC1=NN(C(=C1C(=O)NC2=CC=CC=C2C(C)CC(C)C)F)C;
Properties
Chemical formula	C18H24FN3O
Molar mass	317.408 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Penflufen is a fungicide which was produced and patented by Bayer AG in 2006 and is used for crop protection from fungi.^[1]^[2] Penflufen is a new generation succinate-dehydrogenase inhibitor, which blocks the electron transport at complex II in the mitochondrial respiration chain.^[3] The European Chemical Agency (ECHA) has also approved the use of penflufen as a biocide in wood preservation while labelling it to be a suspected carcinogen.^[4]

References

^ Tian, Fajun; Liu, Xingang; Wu, Yanbing; Xu, Jun; Dong, Fengshou; Wu, Xiaohu; Zheng, Yongquan (December 2016). "Simultaneous determination of penflufen and one metabolite in vegetables and cereals using a modified quick, easy, cheap, effective, rugged, and safe method and liquid chromatography coupled to tandem mass spectrometry". Food Chemistry. 213: 410–416. doi:10.1016/j.foodchem.2016.06.117. ISSN 0308-8146. PMID 27451198.
^ Russell, Phil (2004-06-01). "14th. International Reinhardsbrunn Symposium, Modern Fungicides and Antifungal Compounds, April 25–29 2004, Friedrichroda, Germany". Outlooks on Pest Management. 15 (3): 115–117. doi:10.1564/15jun09. ISSN 1743-1026.
^ Dewar, Alan M. (2012-06-01). "Crop Protection in Northern Britain: A Review of the Recent Dundee Conference". Outlooks on Pest Management. 23 (3): 100–101. doi:10.1564/23jun02. ISSN 1743-1026.
^ ECHA. "ECHA substance info card on Penflufen". Retrieved October 18, 2024.

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[1] Tian, Fajun; Liu, Xingang; Wu, Yanbing; Xu, Jun; Dong, Fengshou; Wu, Xiaohu; Zheng, Yongquan (December 2016). "Simultaneous determination of penflufen and one metabolite in vegetables and cereals using a modified quick, easy, cheap, effective, rugged, and safe method and liquid chromatography coupled to tandem mass spectrometry". Food Chemistry. 213: 410–416. doi:10.1016/j.foodchem.2016.06.117. ISSN 0308-8146. PMID 27451198.

[2] Russell, Phil (2004-06-01). "14th. International Reinhardsbrunn Symposium, Modern Fungicides and Antifungal Compounds, April 25–29 2004, Friedrichroda, Germany". Outlooks on Pest Management. 15 (3): 115–117. doi:10.1564/15jun09. ISSN 1743-1026.

[3] Dewar, Alan M. (2012-06-01). "Crop Protection in Northern Britain: A Review of the Recent Dundee Conference". Outlooks on Pest Management. 23 (3): 100–101. doi:10.1564/23jun02. ISSN 1743-1026.

[4] ECHA. "ECHA substance info card on Penflufen". Retrieved October 18, 2024.

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