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Pancreatic elastase II

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Pancreatic elastase II
Identifiers
EC no.3.4.21.71
CAS no.75603-19-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Preferential cleavage: Leu-, Met- and Phe-. Hydrolyses elastin

This peptidase from trypsin family is formed by activation of proelastase II from mammalian pancreas by trypsin.

References

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  1. ^ Fletcher TS, Shen WF, Largman C (November 1987). "Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA". Biochemistry. 26 (23): 7256–61. doi:10.1021/bi00397a010. PMID 3427074.
  2. ^ Shirasu Y, Yoshida H, Matsuki S, Takemura K, Ikeda N, Shimada Y, Ozawa T, Mikayama T, Iijima H, Ishida A (December 1987). "Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2". Journal of Biochemistry. 102 (6): 1555–63. doi:10.1093/oxfordjournals.jbchem.a122204. PMID 2834346.
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