PSD3

PSD3
Identifiers
Aliases	PSD3, EFA6R, HCA67, EFA6D, pleckstrin and Sec7 domain containing 3
External IDs	OMIM: 614440; MGI: 1918215; HomoloGene: 87257; GeneCards: PSD3; OMA:PSD3 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) Band 8p22 Start 18,527,303 bp End 19,084,730 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8|8 B3.2-B3.3 Start 67,689,082 bp End 68,212,027 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 endothelial cell cerebellar vermis middle temporal gyrus lateral nuclear group of thalamus parietal lobe postcentral gyrus entorhinal cortex Achilles tendon superior frontal gyrus Top expressed in subiculum Region I of hippocampus proper cingulate gyrus primary motor cortex anterior amygdaloid area lobe of cerebellum prefrontal cortex cerebellar vermis medial dorsal nucleus mammillary body More reference expression data BioGPS More reference expression data
Gene ontology Molecular function guanyl-nucleotide exchange factor activity Cellular component synapse membrane cell junction postsynaptic density postsynaptic membrane plasma membrane ruffle membrane cell projection Biological process regulation of ARF protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23362 234353 Ensembl ENSG00000156011 ENSMUSG00000030465 UniProt Q9NYI0 Q2PFD7 RefSeq (mRNA) NM_015310 NM_206909 NM_001362819 NM_027626 NM_030263 NM_177698 RefSeq (protein) NP_056125 NP_996792 NP_001349748 NP_081902 NP_084539 NP_808366 Location (UCSC) Chr 8: 18.53 – 19.08 Mb Chr 8: 67.69 – 68.21 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

PH and SEC7 domain-containing protein 3 is a protein that in humans is encoded by the PSD3 gene.

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Pils D, Horak P, Gleiss A, et al. (2006). "Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival". Cancer. 104 (11): 2417–29. doi:10.1002/cncr.21538. PMID 16270321. S2CID 26030376.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang Y, Han KJ, Pang XW, et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. doi:10.4049/jimmunol.169.2.1102. PMID 12097419.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.