PLSCR2

PLSCR2
Identifiers
Aliases	PLSCR2, phospholipid scramblase 2
External IDs	OMIM: 607610; HomoloGene: 124471; GeneCards: PLSCR2; OMA:PLSCR2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	146,495,991 bp
RNA expression pattern
	Top expressed in
	sperm; ; testicle; ; left testis; ; right testis; ; granulocyte; ; monocyte; ; islet of Langerhans; ; body of pancreas; ; gallbladder; ; rectum;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	phospholipid scramblase activity; calcium ion binding; metal ion binding;
Cellular component	integral component of membrane; plasma membrane; membrane; nucleus;
Biological process	plasma membrane phospholipid scrambling;
	Sources:Amigo / QuickGO
Orthologs
	57047
	n/a
	ENSG00000163746
	n/a
	Q9NRY7
	n/a
	NM_001199978; NM_001199979; NM_020359
	n/a
	NP_001186907; NP_001186908; NP_065092
	n/a
	Wikidata
View/Edit Human

Phospholipid scramblase 2, also known as Ca²⁺-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.^[3]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163746 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: phospholipid scramblase 2".
^ Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. doi:10.1016/S0005-2736(00)00236-4. PMID 10930526.

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Sahu SK, Aradhyam GK, Gummadi SN (2009). "Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell". Biochim. Biophys. Acta. 1790 (10): 1274–81. doi:10.1016/j.bbagen.2009.06.008. PMID 19540310.
Yu A, McMaster CR, Byers DM, et al. (2003). "Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1". J. Biol. Chem. 278 (11): 9706–14. doi:10.1074/jbc.M204614200. PMID 12509439.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163746 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: phospholipid scramblase 2".

[pmid10930526-4] Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. doi:10.1016/S0005-2736(00)00236-4. PMID 10930526.

[1]

[2]

[3]

[4]

PLSCR2

See also

References

Further reading