Ophidascaris robertsi
| Ophidascaris robertsi | |
|---|---|
Scientific classification 
| |
| Domain: | Eukaryota |
| Kingdom: | Animalia |
| Phylum: | Nematoda |
| Class: | Chromadorea |
| Order: | Ascaridida |
| Family: | Ascarididae |
| Genus: | Ophidascaris |
| Species: | O. robertsi
|
| Binomial name | |
| Ophidascaris robertsi (Sprent & Mines, 1960)[1]
| |
| Synonyms[1] | |
|
Amplicaecum robertsi Sprent & Mines, 1960[2] | |
Ophidascaris robertsi is a nematode (also known as roundworm)[3] usually parasitic in the carpet python (Morelia spilota).[4] It is found in Australia and Papua New Guinea. Pythons serve as the typical hosts for Ophidascaris robertsi, which has an indirect life cycle. The adult parasites develop nodular masses in the oesophagus and stomach of carpet pythons and place a small piece of their anterior bodies into the nodules that protrude from the digestive mucosa. When endemic parasites like Ophidascaris robertsi infect local fauna, the pathological changes that follow are frequently self-limiting or do not result in illness.[5]
Description
[edit]Identification of Ophidascaris robertsi from closely related species such as Ophidascaris moreliae is noted to be difficult, depending on the morphology of the egg surface, if cervical alae or post-oesophageal caeca are present, and the shape of the lips.[6]
Hosts
[edit]Reported infections in pythons include Antaresia childreni (children's python), Aspidites melanocephalus (black-headed python), Aspidites ramsayi (woma python), and Morelia spilota (carpet python).[6] There are also reports of infections in a sugar glider (Petaurus breviceps), a koala (Phascolarctos cinereus), a bandicoot (Perameles nasuta) and in other small to medium-sized marsupial species.[7][8][9] One case report of zoonotic infection in a human brain from Australia during 2021–22 was reported in August 2023.[4][10]
A 2021 study on host loss in parasite species used Ophidascaris robertsi as one of the subject taxa.[11]
Human infection
[edit]In June 2022, a neurosurgeon in an Australian hospital found a roundworm in a woman's brain while investigating her mysterious symptoms.[4] The woman initially reported diarrhea and abdominal pain, along with night sweats and dry cough, and was originally diagnosed with a rare lung infection.[12] Though her symptoms improved with treatment, she subsequently returned with symptoms of fever and cough, resulting in an additional diagnosis of a blood disorder. Worsening symptoms of forgetfulness and depression resulted in an MRI that revealed a brain lesion. The biopsy resulted in the discovery and extraction of the live worm.[12] This was the first known instance of such an occurrence, as this type of worm had never been identified as a human parasite before.[4][10][13] The woman, who lived near carpet python habitat and foraged for native vegetation to cook, was believed to have been exposed by consuming the roundworm’s eggs. These eggs, which were commonly shed in snake droppings due to the snakes' diet of infected animals, likely contaminated the grass eaten by small mammals.[4][13][3] Doctors theorize that the various symptoms experienced by the patient resulted from the migration of the parasitic eggs and larva from the bowel, through various other organs, before arriving in the brain.[12]
References
[edit]- ^ a b "Species Ophidascaris robertsi (Sprent & Mines, 1960)". Australian Faunal Directory. Australian Biological Resources Study. 2023. Retrieved 28 August 2023.
- ^ Sprent, J. F. A.; Mines, J. J. (1960). "A new species of Amplicaecum (Nematoda) from the carpet snake (Morelia argus variegatus): with a re-definition and a key for the genus". Parasitology. 50 (1–2): 183–198. doi:10.1017/S0031182000025282. PMID 13833462. S2CID 20230177.
- ^ a b McGuirk, Rod (2023-08-29), "Neurosurgeon investigating patient's mystery symptoms plucks a worm from woman's brain in Australia", Associated Press, retrieved 2023-10-14
- ^ a b c d e Hossein ME, Kennedy KJ, Wilson HL, Spratt D, Koehler A, Gasser RB, Šlapeta J, Hawkins CA, Bandi HP, Senanayake SN (Sep 2023). "Human neural larva migrans caused by Ophidascaris robertsi ascarid". Emerging Infectious Diseases. 29 (9): 1900–1903. doi:10.3201/eid2909.230351. PMC 10461669. PMID 37610238. S2CID 261073909.
- ^ Gonzalez‐Astudillo, Viviana; Knott, Lyn; Valenza, Ludovica; Henning, Joerg; Allavena, Rachel (June 2019). "Parasitism by Ophidascaris robertsi with associated pathology findings in a wild koala ( Phascolarctos cinereus )". Veterinary Record Case Reports. 7 (2). doi:10.1136/vetreccr-2019-000821. S2CID 164545824.
- ^ a b Barton, Diane P.; Jones, Hugh I. (2018). "Nematodes from northern Australian reptiles" (PDF). Northern Territory Naturalist. 28: 43–60.
- ^ Agúndez, MG; Rodríguez, JE; Juan-Sallés, C; Spratt, DM (Dec 2014). "First report of parasitism by Ophidascaris robertsi (Nematoda) in a sugar glider (Petaurus breviceps, Marsupialia)". Journal of Zoo and Wildlife Medicine. 45 (4): 984–986. doi:10.1638/2014-0107.1. PMID 25632698. S2CID 38724780.
- ^ Gonzalez‐Astudillo, Viviana; Knott, Lyn; Valenza, Ludovica; Henning, Joerg; Allavena, Rachel (2019). "Parasitism by Ophidascaris robertsi with associated pathology findings in a wild koala (Phascolarctos cinereus)". Veterinary Record Case Reports. 7 (2): e000821. doi:10.1136/vetreccr-2019-000821. S2CID 164545824.
- ^ MacGregor, Christopher I.; Wood, Jeff T.; Dexter, Nick; Lindenmayer, David B. (2013). "Home range size and use by the long-nosed bandicoot (Perameles nasuta) following fire". Australian Mammalogy. 35 (2): 206. doi:10.1071/AM12032. hdl:1885/64571.
- ^ a b Phil Mercer (29 August 2023). "Live worm found in Australian woman's brain in world first". BBC News, Sydney. Retrieved 29 August 2023.
- ^ Farrell, M.J.; Park, A.W.; Cressler, C.E.; Dallas, T.; Huang, S.; Mideo, N.; Morales-Castilla, I.; Davies, T.J.; Stephens, P. (2021). "The ghost of hosts past: impacts of host extinction on parasite specificity". Philosophical Transactions of the Royal Society B. 376 (1837). doi:10.1098/rstb.2020.0351. PMC 8450631. PMID 34538147. S2CID 237565364.
- ^ a b c "She Was Depressed and Forgetful. It Was the Worm in Her Brain". New York Times. 2023-08-29. Retrieved 2023-09-01.
- ^ a b Mole, Beth (2023-08-28). "Woman's mystery illness turns out to be 3-inch snake parasite in her brain". Ars Technica. Retrieved 2023-08-30.