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Nucleoside oxidase

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Nucleoside oxidase
Identifiers
EC no.1.1.3.28
CAS no.82599-71-1
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Nucleoside oxidase (EC 1.1.3.28) is an enzyme with systematic name nucleoside:oxygen 5'-oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

inosine + O2 9-riburonosylhypoxanthine + H2O
(1a) 2 inosine + O2 2 5'-dehydroinosine + 2 H2O
(1b) 2 5'-dehydroinosine + O2 2 9-riburonosylhypoxanthine

This enzyme could use other purine and pyrimidine nucleosides (as well as 2'-deoxynucleosides) as substrates.

References

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  1. ^ Isono Y, Sudo T, Hoshino M (1989). "Purification and reaction of a new enzyme, nucleoside oxidase". Agric. Biol. Chem. 53: 1663–1669. doi:10.1271/bbb1961.53.1663.
  2. ^ Isono Y, Sudo T, Hoshino M (1989). "Properties of a new enzyme, nucleoside oxidase, from Pseudomonas maltophilia LB-86". Agric. Biol. Chem. 53: 1671–1677. doi:10.1271/bbb1961.53.1671.
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