Norma Andrews
Norma W. Andrews is a cell biologist and professor at the University of Maryland Department of Cell Biology and Molecular Genetics. She chaired the department from 2009 to 2014.[1]
Education and career
[edit]Norma Andrews received her B.S. in 1977 and Ph.D. in 1983, both from the University of São Paulo.[2] She then went on to a postdoctoral fellowship in the laboratory of Victor Nussenzweig at New York University, which she completed in 1990.[2] She then began her own laboratory at Yale University, where she joined the Department of Cell Biology and the Section of Microbial Pathogenesis becoming a Full Professor in 1999.[2] In 2009, Andrews moved her lab to the University of Maryland to chair the Department of Cell Biology and Molecular Genetics.[1] She stepped down from that position in 2014.[1]
Research
[edit]Andrews' research has focused on the cell biology of mammalian cells and their response to intracellular parasitic eukaryotes such as Trypanosoma cruzi and Leishmania.[3] Her group is known for discovering and characterizing calcium-dependent exocytosis of lysosomes in mammalian cells, and its role in repair of the plasma membrane.[2][3]
Notable publications
[edit]- Idone V, Tam C... Andrews NW (2008). Repair of injured plasma membrane by rapid Ca2+ dependent endocytosis. Journal of Cell Biology. 180(5): pgs. 905-914
- Reddy A, Caler EV, Andrews NW (2001). Plasma membrane repair is mediated by Ca2+-regulated exocytosis of lysosomes. Cell. 106(2): pgs. 157-169
- Martinez I, Chakrabarti S... Andrews NW (2000). Synaptotagmin vii regulated Ca2+-dependent exocytosis of lysosomes in fibroblasts. Journal of Cell Biology. 148(6): pgs. 1141-1149
- Rodriguez A, Webster P... Andrews NW (1997). Lysosomes behave as Ca2+-regulated exocytic vesicles in fibroblasts and epithelial cells. Journal of Cell Biology. 137(1): pgs. 93-104
- Tardieux I, Webster P... Andrews NW (1992). Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells. Cell. 71(7): pgs. 1117-1130
- Tam C, Idone V... Andrews NW (2010). Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair. Journal of Cell Biology. 189(6): pgs. 1027-1038
References
[edit]- ^ a b c "Current Lab Members". Andrews Lab - University of Maryland. Retrieved 16 July 2019.
- ^ a b c d "Norma Andrews". iBiology. Retrieved 16 July 2019.
- ^ a b "Norma W. Andrews". University of Maryland. Retrieved 16 July 2019.
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