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NOM1

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NOM1
Identifiers
AliasesNOM1, C7orf3, PPP1R113, SGD1, nucleolar protein with MIF4G domain 1
External IDsOMIM: 611269; MGI: 1861749; HomoloGene: 39776; GeneCards: NOM1; OMA:NOM1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_138400
NM_001353366

NM_001033457

RefSeq (protein)

NP_612409
NP_001340295

NP_001028629

Location (UCSC)Chr 7: 156.95 – 156.97 MbChr 5: 29.64 – 29.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleolar protein with MIF4G domain 1 is a protein that in humans is encoded by the NOM1 gene.[5]

Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases.[6][5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146909Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001569Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Nucleolar protein with MIF4G domain 1". Retrieved 2011-09-27.
  6. ^ Simmons HM, Ruis BL, Kapoor M, Hudacek AW, Conklin KF (February 2005). "Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia". Gene. 347 (1): 137–145. doi:10.1016/j.gene.2004.12.027. PMID 15715967.

Further reading

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