Morogoro virus
| Morogoro virus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Negarnaviricota |
| Class: | Ellioviricetes |
| Order: | Bunyavirales |
| Family: | Arenaviridae |
| Genus: | Mammarenavirus |
| Virus: | Morogoro virus
|
Morogoro virus is an East African arenavirus infecting the multimammate mouse (Mastomys natalensis).[1] The virus is genetically closely related to Lassa virus, known to cause Lassa fever in humans. Morogoro virus, however, does not seem to infect humans.[1] Transmission of Morogoro virus between mice is assumed to occur via direct and indirect contact.[2] Infected animals pass a latent period of 7 days and subsequently shed the virus for about 30 days, after which they recover and develop lifelong antibodies.[3] Transmission may also be possible from infected mothers to offspring and through sexual contact, as this has been suggested for other arenaviruses.[4][5]
References
[edit]- ^ a b Günther S, Hoofd G, Charrel R, Röser C, Becker-Ziaja B, Lloyd G, Sabuni C, Verhagen R, van der Groen G, Kennis J, Katakweba A, Machang'u R, Makundi R, Leirs H (December 2009). "Mopeia virus-related arenavirus in natal multimammate mice, Morogoro, Tanzania". Emerg Infect Dis. 15 (12): 2008–2012. doi:10.3201/eid1512.090864. PMC 3044542. PMID 19961688.
- ^ Borremans B, Leirs H, Gryseels S, Günther S, Makundi R, de Bellocq JG (August 2011). "Presence of Mopeia virus, an African arenavirus, related to biotope and individual rodent host characteristics: implications for virus transmission". Vector Borne Zootic Dis. 11 (8): 1125–1131. doi:10.1089/vbz.2010.0010. PMID 21142956.
- ^ Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van Houtte N, Günther S, Leirs H (29 May 2015). "Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis". Sci Rep. 5: 10445. Bibcode:2015NatSR...510445B. doi:10.1038/srep10445. PMC 4448520. PMID 26022445.
- ^ Fichet-Calvet E, Becker-Ziaja B, Koivogui L, Günther S (September 2014). "Lassa serology in natural populations of rodents and horizontal transmission". Vector Borne Zoonotic Dis. 14 (9): 665–674. doi:10.1089/vbz.2013.1484. PMC 4170823. PMID 25229705.
- ^ Webb PA, Justines G, Johnson KM (1975). "Infection of wild and laboratory animals with Machupo and Latino viruses". Bull World Health Organ. 52 (4–6): 493–499. PMC 2366657. PMID 182399.