Michaelis–Becker reaction
The Michaelis–Becker reaction is the reaction of a hydrogen (thio)phosphonate with a base, followed by a nucleophilic substitution of phosphorus on a haloalkane, to give an alkyl (thio)phosphonate.[1] Yields of this reaction are often lower than the corresponding Michaelis–Arbuzov reaction.[2][3]
Further reading
[edit]- Savignac, Philippe; Iorga, Bogdan (2003). Modern phosphonate chemistry. CRC Press. ISBN 978-0-8493-1099-7.
References
[edit]- ^ Almasi, Lucreţia (1971). "The Sulfur–Phosphorus Bond". In Senning, Alexander (ed.). Sulfur in Organic and Inorganic Chemistry. Vol. 1. New York: Marcel Dekker. p. 56. ISBN 0-8247-1615-9. LCCN 70-154612.
- ^ Fletcher, M.D. Organophosphorus Reagents; Murphy, P.J. Ed.; University Press: Oxford, 2002; pp. 185.
- ^ Murphy, Dr. Patrick J (2004). Organophosphorus reagents: a practical approach in chemistry. Oxford University Press. ISBN 978-0-19-850262-3.