Methylenomycin A
Appearance
Names | |
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Preferred IUPAC name
(1S,2R,5S)-1,5-Dimethyl-3-methylidene-4-oxo-6-oxabicyclo[3.1.0]hexane-2-carboxylic acid | |
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3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H10O4 | |
Molar mass | 182.19 g mol−1 |
Boiling point | 341.2 °C (646.2 °F; 614.3 K) |
Hazards | |
Flash point | 141.2 °C (286.2 °F; 414.3 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Methylenomycin A is a cyclopentanone derived antibiotic produced by Streptomyces coelicolor A3(2) that is effective against both Gram-negative and Gram-positive bacteria.[1][2] Methylenomycins are naturally produced in two variants: A and B.[citation needed]
See also
[edit]References
[edit]- ^ Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. doi:10.1128/jb.178.11.3221-3231.1996. PMC 178074. PMID 8655502.
- ^ Hobbs G, Obanye AI, Petty J, et al. (March 1992). "An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2)". J. Bacteriol. 174 (5): 1487–94. doi:10.1128/jb.174.5.1487-1494.1992. PMC 206543. PMID 1537793.