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Protein-coding gene in the species Homo sapiens
Matrilin-2 is a matrilin protein that in humans is encoded by the MATN2 gene .[ 5] [ 6] [ 7]
This gene encodes a member of the von Willebrand factor A domain containing protein family. This family of proteins is thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This protein contains five von Willebrand factor A domains. The specific function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000132561 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022324 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Deak F, Piecha D, Bachrati C, Paulsson M, Kiss I (May 1997). "Primary structure and expression of matrilin-2, the closest relative of cartilage matrix protein within the von Willebrand factor type A-like module superfamily" . J Biol Chem . 272 (14): 9268–74. doi :10.1074/jbc.272.14.9268 PMID 9083061 . ^ Mates L, Korpos E, Deak F, Liu Z, Beier DR, Aszodi A, Kiss I (Mar 2002). "Comparative analysis of the mouse and human genes (Matn2 and MATN2) for matrilin-2, a filament-forming protein widely distributed in extracellular matrices". Matrix Biol . 21 (2): 163–74. doi :10.1016/S0945-053X(01)00194-9 . PMID 11852232 . ^ a b "Entrez Gene: MATN2 matrilin 2" .
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