MOGAT3

MOGAT3
Identifiers
Aliases	MOGAT3, DC7, DGAT2L7, MGAT3, DGAT2L2, monoacylglycerol O-acyltransferase 3
External IDs	OMIM: 610184; HomoloGene: 80517; GeneCards: MOGAT3; OMA:MOGAT3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	101,201,038 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of ileum; ; rectum; ; right lobe of liver; ; duodenum; ; testicle; ; jejunal mucosa; ; mucosa of sigmoid colon; ; appendix; ; epithelium of colon;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	acyltransferase activity; acyltransferase activity, transferring groups other than amino-acyl groups; transferase activity; diacylglycerol O-acyltransferase activity; 2-acylglycerol O-acyltransferase activity;
Cellular component	membrane; integral component of membrane; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	lipid metabolism; glycerol metabolic process; triglyceride biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	346606
	n/a
	ENSG00000106384
	n/a
	Q86VF5
	n/a
	NM_001287147; NM_178176
	n/a
	NP_001274076; NP_835470
	n/a
	Wikidata
View/Edit Human

Monoacylglycerol O-acyltransferase 3 is a protein that in humans is encoded by the MOGAT3 gene.^[3]

Function

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106384 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Monoacylglycerol O-acyltransferase 3".
^ Cheng D, Nelson TC, Chen J, Walker SG, Wardwell-Swanson J, Meegalla R, Taub R, Billheimer JT, Ramaker M, Feder JN (Apr 2003). "Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption". The Journal of Biological Chemistry. 278 (16): 13611–4. doi:10.1074/jbc.C300042200. PMID 12618427.

Function

References

Further reading