MIR561

MicroRNA 561 is a protein that in humans is encoded by the MIR561 gene. ^[1]

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].

References

^ "Entrez Gene: MicroRNA 561". Retrieved 2014-07-13.

v t e Types of RNA
Protein synthesis	Messenger RNA Ribosomal RNA Signal recognition particle RNA Transfer RNA Transfer-messenger RNA
RNA processing	Small nuclear RNA Small nucleolar RNA Guide RNA RNase P RNase MRP Y RNA
Gene regulation	Antisense RNA Cis-natural antisense transcript CRISPR RNA Long noncoding RNA MicroRNA Piwi-interacting RNA Repeat-associated siRNA Small interfering RNA Small temporal RNA Trans-acting siRNA Short hairpin RNA
Cis-regulatory elements	Riboswitch SECIS element
Parasites	Retrotransposon Reverse transcribing virus RNA virus Viroid
Other	Telomerase RNA Vault RNA List of RNAs

Function

References

Further reading