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MINPP1

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MINPP1
Identifiers
AliasesMINPP1, HIPER1, MINPP2, MIPP, multiple inositol-polyphosphate phosphatase 1, PCH16
External IDsOMIM: 605391; MGI: 1336159; HomoloGene: 37980; GeneCards: MINPP1; OMA:MINPP1 - orthologs
EC number3.1.3.80
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001178117
NM_001178118
NM_004897

NM_010799

RefSeq (protein)

NP_001171588
NP_001171589
NP_004888

NP_034929

Location (UCSC)Chr 10: 87.5 – 87.55 MbChr 19: 32.46 – 32.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Multiple inositol polyphosphate phosphatase 1 is an enzyme that in humans is encoded by the MINPP1 gene.[5][6]

MINPP1 hydrolyzes the abundant metabolites inositol pentakisphosphate and inositol hexakisphosphate and, like PTEN (MIM 601728), has the ability to remove 3-phosphate from inositol phosphate substrates.[supplied by OMIM][6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000107789Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024896Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chi H, Tiller GE, Dasouki MJ, Romano PR, Wang J, O'keefe RJ, Puzas JE, Rosier RN, Reynolds PR (May 1999). "Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19". Genomics. 56 (3): 324–36. doi:10.1006/geno.1998.5736. PMID 10087200.
  6. ^ a b "Entrez Gene: MINPP1 multiple inositol polyphosphate histidine phosphatase, 1".

Further reading

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