MC21-B

MC21-B
Names
	Preferred IUPAC name 2,2′,3-Tribromo[1,1′-biphenyl]-4,4′-dicarboxylic acid
	Other names 2,2′,3-Tribromobiphenyl-4,4′-dicarboxylic acid
Identifiers
3D model (JSmol)	Interactive image;
PubChem CID	44181740;
CompTox Dashboard (EPA)	DTXSID301028290 ;
	InChI InChI=1S/C14H7Br3O4/c15-10-5-6(13(18)19)1-2-7(10)8-3-4-9(14(20)21)12(17)11(8)16/h1-5H,(H,18,19)(H,20,21) Key: BTFCVLPFWWMQRI-UHFFFAOYSA-N;
	SMILES OC(=O)c1cc(Br)c(cc1)c2c(Br)c(Br)c(cc2)C(=O)O;
Properties
Chemical formula	C14H7Br3O4
Molar mass	478.918 g·mol−1
Appearance	White powder
Solubility in water	Sol. MeOH, CHCl3; insol. H2O, hexane
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

MC21-B is an antibiotic isolated from the O-BC30T strain of a marine bacterium, Pseudoalteromonas phenolica.^[1] MC21-B is cytotoxic to human leukaemia cells and human normal dermal fibroblasts.^[2]

References

^ Isnansetyo, A.; Kamei, Y. (2009). "Anti-methicillin-resistant Staphylococcus aureus (MRSA) activity of MC21-B, an antibacterial compound produced by the marine bacterium Pseudoalteromonas phenolica O-BC30T". International Journal of Antimicrobial Agents. 34 (2): 131–135. doi:10.1016/j.ijantimicag.2009.02.009. PMID 19329285.
^ Rahman, H.; Austin, B.; Mitchell, W. J.; Morris, P. C.; Jamieson, D. J.; Adams, D. R.; Spragg, A. M.; Schweizer, M. (2010). "Novel Anti-Infective Compounds from Marine Bacteria". Marine Drugs. 8 (3): 498–518. doi:10.3390/md8030498. PMC 2857357. PMID 20411112.

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