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Protein-coding gene in the species Homo sapiens
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA is an enzyme that in humans is encoded by the MAN1A1 gene .[ 5] [ 6]
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the removal of 3 distinct mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000111885 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003746 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Bause E, Bieberich E, Rolfs A, Volker C, Schmidt B (Dec 1993). "Molecular cloning and primary structure of Man9-mannosidase from human kidney" . Eur J Biochem . 217 (2): 535–40. doi :10.1111/j.1432-1033.1993.tb18274.x PMID 8223597 . ^ a b "Entrez Gene: MAN1A1 mannosidase, alpha, class 1A, member 1" .
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