From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Myosin phosphatase Rho-interacting protein is an enzyme that in humans is encoded by the MPRIP gene .[ 5] [ 6]
M-RIP has been shown to interact with RHOA .[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000133030 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005417 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 5 (6): 355–64. doi :10.1093/dnares/5.6.355 . PMID 10048485 .
^ "Entrez Gene: M-RIP myosin phosphatase-Rho interacting protein" .
^ Gebbink MF, Kranenburg O, Poland M, van Horck FP, Houssa B, Moolenaar WH (Jun 1997). "Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology" . J. Cell Biol . 137 (7): 1603–13. doi :10.1083/jcb.137.7.1603 . PMC 2137826 . PMID 9199174 .
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806. doi :10.1101/gr.6.9.791 . PMID 8889548 .
Gebbink MF, Kranenburg O, Poland M, van Horck FP, Houssa B, Moolenaar WH (1997). "Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology" . J. Cell Biol . 137 (7): 1603–13. doi :10.1083/jcb.137.7.1603 . PMC 2137826 . PMID 9199174 .
Surks HK, Richards CT, Mendelsohn ME (2004). "Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA" . J. Biol. Chem . 278 (51): 51484–93. doi :10.1074/jbc.M305622200 . PMID 14506264 .
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Mulder J, Ariaens A, van den Boomen D, Moolenaar WH (2005). "p116Rip targets myosin phosphatase to the actin cytoskeleton and is essential for RhoA/ROCK-regulated neuritogenesis" . Mol. Biol. Cell . 15 (12): 5516–27. doi :10.1091/mbc.E04-04-0275 . PMC 532030 . PMID 15469989 .
Koga Y, Ikebe M (2005). "p116Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA" . J. Biol. Chem . 280 (6): 4983–91. doi :10.1074/jbc.M410909200 . PMID 15545284 .
Benzinger A, Muster N, Koch HB, Yates JR, Hermeking H (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer" . Mol. Cell. Proteomics . 4 (6): 785–95. doi :10.1074/mcp.M500021-MCP200 . PMID 15778465 .
Surks HK, Riddick N, Ohtani K (2006). "M-RIP targets myosin phosphatase to stress fibers to regulate myosin light chain phosphorylation in vascular smooth muscle cells" . J. Biol. Chem . 280 (52): 42543–51. doi :10.1074/jbc.M506863200 . PMID 16257966 .
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 . PMID 17081983 . S2CID 7827573 .
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