Lunamarine
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| Preferred IUPAC name
2-(2H-1,3-Benzodioxol-5-yl)-7-methoxy-1-methylquinolin-4(1H)-one | |
| Identifiers | |
3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C18H15NO14 | |
| Molar mass | 469.311 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Lunamarine (punarnavine) is a quinolone alkaloid present in Boerhavia diffusa (punarnava).
The compound has shown some in vitro anticancer,[1] antiestrogenic,[2] immunomodulatory,[3] and anti-amoebic activity (particularly against Entamoeba histolytica).[4]
References
[edit]- ^ Manu K.A.; Kuttan G. (2009). "Punarnavine induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB signaling". Asian Pacific Journal of Cancer Prevention. 10 (6): 1031–1037. PMID 20192578.
- ^ Sreeja S.; Sreeja S. (2009). "An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts". Journal of Ethnopharmacology. 126 (2): 221–225. doi:10.1016/j.jep.2009.08.041. PMID 19723573.
- ^ Manu K.A.; Kuttan G. (2009). "Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa". Immunopharmacology and Immunotoxicology. 31 (3): 377–387. doi:10.1080/08923970802702036. PMID 19555203. S2CID 2066582.
- ^ Sohni YR.; Kaimal P.; Bhatt RM. (Jan 1995). "The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo". Journal of Ethnopharmacology. 45 (1): 43–52. doi:10.1016/0378-8741(94)01194-5. PMID 7739226.
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