Kallidin
 | This article relies largely or entirely on a single source. (February 2017) |
| |
| |
| Names | |
|---|---|
| IUPAC name
L-Lysyl-L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
| ECHA InfoCard | 100.005.853 |
| MeSH | Kallidin |
PubChem CID
|
|
| UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
| Properties | |
| C56H85N17O12 | |
| Molar mass | 1188.403 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
| |
Kallidin is a bioactive kinin formed in response to injury from kininogen precursors through the action of kallikreins.[1]
Kallidin is a decapeptide whose sequence is H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. It can be converted to bradykinin by the aminopeptidase enzyme.
It can be a substrate for carboxypeptidase M and N.[2]
Kallidin is identical to bradykinin with an additional lysine residue added at the N-terminal end and signals through the bradykinin receptor.
References
[edit]- ^ Campbell, Duncan John (2013). "Chapter 188 - Bradykinin Peptides". In Kastin, Abba J. (ed.). Handbook of Biologically Active Peptides (2nd ed.). Elsevier. doi:10.1016/C2010-0-66490-X. ISBN 978-0-12-385095-9 – via ScienceDirect.
- ^ Stefan Offermanns; Walter Rosenthal (2008). Encyclopedia of Molecular Pharmacology. Springer. pp. 673–. ISBN 978-3-540-38916-3. Retrieved 11 December 2010.
.svg){kind=small} | This biochemistry article is a stub. You can help Wikipedia by expanding it. |