Kalium Database
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Type of site | Biomedical database |
|---|---|
| Available in | |
| Founded | Russian Academy of Sciences, Moscow, Russia |
| Created by | Alexey I. Kuzmenkov Nikolay A. Krylov Daria A. Yureva Valentin M. Tabakmakher Anton O. Chugunov Alexander A. Vassilevski |
| URL | kaliumdb |
| Launched | April 16, 2016 |
| Current status | Active |
The Kalium Database is a manually curated biomedical database on K+ channel ligands found in the venom of scorpions, spiders, sea anemones, cone snails, snakes, centipedes, bees, and more.[1] The first release of the Kalium Database was dedicated to scorpion toxins only,[2] while its second release (Kalium 2.0) included toxins from other living organisms.[3] The most recent update (Kalium 3.0) added information on their artificial derivatives. The Kalium Database is meant to assist structural biologists, toxinologists, pharmacologists, medicinal chemists, and other researchers in their pursuit to develop new drugs for cardiovascular and neurological diseases.
References
[edit]- ^ Kuzmenkov AI, Grishin EV, Vassilevski AA (Dec 2015). "Diversity of Potassium Channel Ligands: Focus on Scorpion Toxins". Biochemistry (Mosc). 80 (13): 1764–99. doi:10.1134/S0006297915130118. PMID 26878580. S2CID 254277851.
- ^ Kuzmenkov AI, Krylov NA, Chugunov AO, Grishin EV, Vassilevski AA (Apr 2016). "Kalium: a database of potassium channel toxins from scorpion venom". Database (Oxford). baw056: baw056. doi:10.1093/database/baw056. PMC 4834203. PMID 27087309.
- ^ Tabakmakher VM, Krylov NA, Kuzmenkov AI, Efremov RG, Vassilevski AA (May 2019). "Kalium 2.0, a comprehensive database of polypeptide ligands of potassium channels". Sci Data. 6 (1): 73. Bibcode:2019NatSD...6...73T. doi:10.1038/s41597-019-0074-x. PMC 6536513. PMID 31133708.
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